SAFO Meaning and
Definition
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SAFO stands for "Sickle Cell Anemia, Fetomaternal Hemorrhage and Organic Acidemias." It refers to a diagnostic screening test used in newborns to identify various inherited conditions that can potentially cause severe health issues or even be life-threatening if left untreated. SAFO is a panel of metabolic disorders that includes three major categories of conditions: sickle cell anemia, fetomaternal hemorrhage, and organic acidemias.
Sickle cell anemia is a genetic blood disorder in which abnormal hemoglobin causes red blood cells to become deformed, leading to various complications such as anemia, pain crises, and organ damage. Fetomaternal hemorrhage, on the other hand, refers to the condition where fetal blood, specifically fetal red blood cells, enters the maternal circulation, potentially causing complications if there is a Rh blood type incompatibility between the mother and the baby. Organic acidemias are a group of inherited disorders that occur due to metabolic defects leading to the accumulation of toxic substances in the body, causing a range of symptoms including developmental delays, seizures, and even death if not managed promptly.
SAFO screening involves a blood test shortly after birth, commonly done via a heel prick. It aims to detect the presence of these disorders early, enabling timely medical intervention and management to ensure the best possible outcomes for affected infants. Although SAFO is an acronym that combines these three conditions together, each component represents a distinct group of disorders. Newborn screening programs often incorporate SAFO as part of their routine testing to identify affected infants promptly, facilitating early intervention and improving their long-term health.
Common Misspellings for SAFO
- saf0
- zsafo
- xsafo
- sxafo
- saf0o
- safo0
- saf9o
- safo9
- safoo
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