CHLORIDE BICARBONATE EXCHANGERS Meaning and
Definition
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Chloride bicarbonate exchangers, also known as bicarbonate chloride exchangers, are a class of membrane proteins that play a crucial role in the transport of chloride and bicarbonate ions across cell membranes. These exchangers are primarily found in epithelial cells lining the digestive, renal, and respiratory systems.
The function of chloride bicarbonate exchangers is to maintain the balance of chloride and bicarbonate ions in the extracellular and intracellular fluids. They accomplish this by exchanging chloride ions (Cl-) in the cytoplasm with bicarbonate ions (HCO3-) in the extracellular fluid. This exchange is electrogenic, meaning it contributes to the electrical potential difference across the cell membrane, and it is essential for maintaining the pH balance and overall homeostasis of the body.
In the digestive system, chloride bicarbonate exchangers are involved in the secretion of pancreatic fluid, which contains enzymes crucial for digestion. In the kidneys, they regulate the reabsorption and secretion of bicarbonate and chloride ions, thereby controlling the pH and overall electrolyte balance in the body. Additionally, these exchangers are involved in the transport of carbon dioxide across the respiratory epithelium.
Malfunction or mutations in chloride bicarbonate exchangers can lead to various disorders, such as cystic fibrosis, an inherited disease characterized by abnormal transport of chloride ions. Understanding the function and regulation of chloride bicarbonate exchangers is of great importance in developing therapeutic strategies for these disorders.
Common Misspellings for CHLORIDE BICARBONATE EXCHANGERS
- xhloride bicarbonate exchangers
- vhloride bicarbonate exchangers
- fhloride bicarbonate exchangers
- dhloride bicarbonate exchangers
- cgloride bicarbonate exchangers
- cbloride bicarbonate exchangers
- cnloride bicarbonate exchangers
- cjloride bicarbonate exchangers
- culoride bicarbonate exchangers
- cyloride bicarbonate exchangers
- chkoride bicarbonate exchangers
- chporide bicarbonate exchangers
- chooride bicarbonate exchangers
- chliride bicarbonate exchangers
- chlkride bicarbonate exchangers
- chllride bicarbonate exchangers
- chlpride bicarbonate exchangers
- chl0ride bicarbonate exchangers
- chl9ride bicarbonate exchangers
- chloeide bicarbonate exchangers
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