EXPERIMENTAL LUNG INFLAMMATION Meaning and
Definition
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Experimental lung inflammation refers to the induced inflammation of the lungs in laboratory settings for the purpose of scientific investigation. It is a controlled and deliberately initiated condition designed to mimic lung inflammation observed in various diseases, such as asthma, chronic obstructive pulmonary disease (COPD), or acute respiratory distress syndrome (ARDS). The aim of experimental lung inflammation is to study the underlying mechanisms of the inflammatory response, evaluate potential therapeutic interventions and their efficacy, and gain insight into disease pathogenesis.
To induce experimental lung inflammation, various methods can be employed, including exposure to allergens, chemical irritants, or infectious agents. These triggers can stimulate the immune system and cause an inflammatory cascade in the lung tissue, leading to the infiltration of inflammatory cells such as neutrophils, macrophages, and lymphocytes. The resulting inflammation can cause symptoms such as coughing, shortness of breath, and impaired lung function.
This model allows researchers to investigate the cellular and molecular events involved in the inflammatory response, examine the role of specific genes, proteins, and signaling pathways, and test potential anti-inflammatory drugs or therapies. By studying experimental lung inflammation, scientists can gain a deeper understanding of the complex cellular and molecular interactions that contribute to lung diseases, which may lead to the development of new treatment strategies and more effective therapies to alleviate lung inflammation and improve patient outcomes.
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Inflammation of the lungs.
Etymological and pronouncing dictionary of the English language. By Stormonth, James, Phelp, P. H. Published 1874.
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