MUREIN HYDROLASE Meaning and
Definition
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Murein hydrolase, also known as peptidoglycan hydrolase, is an enzyme that plays a crucial role in the degradation and remodeling of bacterial cell walls. It is an important class of enzymes that specifically target the murein or peptidoglycan layer in the cell wall of bacteria.
Murein hydrolases possess the capability to cleave the covalent bonds between the sugar and amino acid components of the murein layer, thus leading to the breakdown of the cell wall structure. These enzymes exhibit various hydrolytic activities, such as endopeptidase, amidase, endo-β-N-acetylglucosaminidase, lytic transglycosylase, and muramidase.
Their activity is essential during various bacterial physiological processes, including cell division, cell wall turnover, and peptidoglycan remodeling. Murein hydrolases also play a crucial role in bacterial survival and pathogenesis by facilitating growth, colonization, and infection.
Due to their importance in bacterial physiology and their involvement in bacterial virulence, murein hydrolases have been a target for antimicrobial drug development. These enzymes have attracted significant research interest in order to understand their structure, function, regulation, and potential as therapeutic targets.
In summary, murein hydrolase is a class of enzymes that degrade the murein or peptidoglycan layer in bacterial cell walls through hydrolysis, playing essential roles in bacterial physiology, survival, and virulence.
Common Misspellings for MUREIN HYDROLASE
- nurein hydrolase
- kurein hydrolase
- jurein hydrolase
- myrein hydrolase
- mhrein hydrolase
- mjrein hydrolase
- mirein hydrolase
- m8rein hydrolase
- m7rein hydrolase
- mueein hydrolase
- mudein hydrolase
- mufein hydrolase
- mutein hydrolase
- mu5ein hydrolase
- mu4ein hydrolase
- murwin hydrolase
- mursin hydrolase
- murdin hydrolase
- murrin hydrolase
- mur4in hydrolase
Etymology of MUREIN HYDROLASE
The word "Murein Hydrolase" has its etymology rooted in the field of microbiology and biochemistry.
1. Murein: Murein refers to the peptidoglycan, a key component of bacterial cell walls. It is a complex network of sugar and amino acid chains that provide structural strength and protection to the bacteria. The term "murein" is derived from the German word "Mauer", meaning wall or barrier. It was coined in 1885 by the German bacteriologist Albert Lehmann when he discovered the bacterial cell wall's composition.
2. Hydrolase: Hydrolase is a term used to describe enzymes that catalyze hydrolysis, a chemical reaction that breaks down compounds through the addition of water.
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