MURINE LEUKEMIA VIRUSES Meaning and
Definition
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Murine Leukemia Viruses (MLVs) are a group of retroviruses that primarily infect mice and are known to cause leukemia and other hematological malignancies. MLVs belong to the family Retroviridae and the genus Gammaretrovirus. These viruses are characterized by their ability to convert their RNA genome into DNA through the action of an enzyme called reverse transcriptase, which allows them to integrate their genetic material into the host cell's DNA and replicate within the infected cells.
Murine Leukemia Viruses have been extensively studied as model systems for understanding the molecular mechanisms of viral replication, tumorigenesis, and immunological responses. They have served as important tools in cancer research, particularly in the study of retroviral-induced leukemia, which has offered insights into the development and progression of human leukemia.
MLVs can be transmitted horizontally, from mouse to mouse, through direct contact or contaminated materials, as well as vertically, from infected mother to offspring during pregnancy or through milk during nursing. Infection with these viruses can lead to a wide range of clinical outcomes, from asymptomatic carrier states to the development of various types of leukemia or lymphoma.
Understanding Murine Leukemia Viruses is of particular importance in veterinary and biomedical research, as well as in the development of vaccines and treatments for human retroviral infections and cancer.
Common Misspellings for MURINE LEUKEMIA VIRUSES
- nurine leukemia viruses
- kurine leukemia viruses
- jurine leukemia viruses
- myrine leukemia viruses
- mhrine leukemia viruses
- mjrine leukemia viruses
- mirine leukemia viruses
- m8rine leukemia viruses
- m7rine leukemia viruses
- mueine leukemia viruses
- mudine leukemia viruses
- mufine leukemia viruses
- mutine leukemia viruses
- mu5ine leukemia viruses
- mu4ine leukemia viruses
- murune leukemia viruses
- murjne leukemia viruses
- murkne leukemia viruses
- murone leukemia viruses
- mur9ne leukemia viruses
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