PERINEURONAL SATELLITE CELLS Meaning and
Definition
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Perineuronal satellite cells, also known as perineuronal oligodendrocytes or perineuronal glial cells, are a specialized type of support cells found in the central nervous system (CNS) closely associated with neurons. They are mainly located in the cerebral cortex, cerebellum, and spinal cord.
These cells have a distinct morphology and are characterized by their close proximity to neuronal cell bodies, specifically encircling the soma or forming satellite-like structures around it. Perineuronal satellite cells have a close functional and symbiotic relationship with the neurons they envelop.
Their primary function is to provide structural and metabolic support to neurons. They help in maintaining the ionic balance and stability of the extracellular environment surrounding neurons by regulating the uptake and release of various ions and neurotransmitters. This plays a crucial role in synaptic transmission and overall neuronal function. Perineuronal satellite cells are also thought to be involved in the myelination of axons, aiding in the insulation and conduction of nerve impulses.
Although still not fully understood, perineuronal satellite cells are believed to have important roles in neuroprotection and plasticity. They have been implicated in various neurological disorders, such as epilepsy and neurodegenerative diseases, highlighting their potential significance in maintaining healthy neuronal function.
Further research and investigation are needed to gain a deeper understanding of perineuronal satellite cells and their intricate interactions with neurons, which could potentially lead to the development of new therapeutic approaches targeting these support cells for the treatment of neurological conditions.
Common Misspellings for PERINEURONAL SATELLITE CELLS
- oerineuronal satellite cells
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- petineuronal satellite cells
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- perjneuronal satellite cells
- perkneuronal satellite cells
- peroneuronal satellite cells
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