PERIPHERAL AUTOIMMUNE DEMYELINATING DISEASE Meaning and
Definition
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Peripheral Autoimmune Demyelinating Disease (PAD) refers to a group of disorders characterized by an abnormal immune system response against the myelin sheath in the peripheral nervous system. The myelin sheath is a protective covering around nerve fibers that facilitates efficient transmission of electrical impulses. In PAD, the immune system mistakenly identifies the myelin as a foreign substance and launches an attack, leading to inflammation and subsequent destruction of the myelin sheath.
These diseases can manifest in various forms, such as Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy (CIDP), both of which result in progressive weakness and impaired sensory function in the extremities. Other PAD subtypes include multifocal motor neuropathy with conduction block (MMN) and peripheral myelin protein 22 (PMP22) duplication neuropathy.
Common symptoms of PAD include muscle weakness, tingling or numbness, loss of coordination, and impaired reflexes. The severity and progression of symptoms can vary between individuals and specific diseases. PAD is typically diagnosed through a combination of clinical examination, nerve conduction studies, and electromyography.
Although the exact causes of PAD are not fully understood, it is believed to arise from an autoimmune response triggered by genetic, environmental, and immunological factors. Treatment options for PAD generally involve suppressing the immune response with various immunomodulating therapies, such as corticosteroids, intravenous immunoglobulin therapy, and plasma exchange. Physical therapy and rehabilitation may also be recommended to manage symptoms and improve quality of life.
Common Misspellings for PERIPHERAL AUTOIMMUNE DEMYELINATING DISEASE
- oeripheral autoimmune demyelinating disease
- leripheral autoimmune demyelinating disease
- -eripheral autoimmune demyelinating disease
- 0eripheral autoimmune demyelinating disease
- pwripheral autoimmune demyelinating disease
- psripheral autoimmune demyelinating disease
- pdripheral autoimmune demyelinating disease
- prripheral autoimmune demyelinating disease
- p4ripheral autoimmune demyelinating disease
- p3ripheral autoimmune demyelinating disease
- peeipheral autoimmune demyelinating disease
- pedipheral autoimmune demyelinating disease
- pefipheral autoimmune demyelinating disease
- petipheral autoimmune demyelinating disease
- pe5ipheral autoimmune demyelinating disease
- pe4ipheral autoimmune demyelinating disease
- perupheral autoimmune demyelinating disease
- perjpheral autoimmune demyelinating disease
- perkpheral autoimmune demyelinating disease
- peropheral autoimmune demyelinating disease
Similar spelling words for PERIPHERAL AUTOIMMUNE DEMYELINATING DISEASE
- Demyelinating Autoimmune Disease Peripheral,
- Demyelinating Autoimmune Disease, Peripheral.
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