SNRNP Meaning and
Definition
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SNRNP stands for Small Nuclear Ribonucleoprotein and refers to a group of proteins that are involved in the processing and maturation of pre-mRNA molecules in eukaryotic cells. These ribonucleoprotein complexes play a crucial role in the splicing of pre-mRNA during gene expression.
Pre-mRNA molecules are transcribed from DNA and contain both coding (exons) and non-coding (introns) regions. The SNRNP complexes recognize and bind to specific sequences at the exon/intron junctions of pre-mRNA molecules. This binding is essential for accurate splicing, which involves the removal of introns and the joining together of exons to produce mature mRNA molecules.
SNRNPs are composed of small nuclear RNA (snRNA) molecules and associated proteins. The snRNA provides the catalytic activity for splicing, while the proteins stabilize the complex and facilitate its binding to the pre-mRNA. The most well-known SNRNP is the spliceosome, which is composed of multiple sequential subcomplexes and carries out the splicing reactions.
Defects or mutations in SNRNP proteins or snRNA molecules can lead to a range of genetic disorders known as spliceosomal or snRNP-related diseases. These disorders are characterized by abnormal splicing of pre-mRNA, which can result in the production of abnormal or non-functional proteins. Some examples of SNRNP-related diseases include spinal muscular atrophy (SMA) and various forms of retinitis pigmentosa.
In summary, SNRNP refers to a group of ribonucleoprotein complexes that play a fundamental role in the splicing and processing of pre-mRNA molecules. These complexes are essential for the accurate and efficient expression of genes in eukaryotic cells.
Common Misspellings for SNRNP
- anrnp
- znrnp
- xnrnp
- dnrnp
- enrnp
- wnrnp
- smrnp
- sjrnp
- shrnp
- snenp
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- shnrnp
- snhrnp
- snernp
- snrenp
- sndrnp
- snrdnp
- snfrnp
- snrfnp
- sntrnp
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- sn5rnp
- snr5np
- sn4rnp
- snr4np
- snrbnp
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- snrn0p
- snrnp0
- nsrnp
- srnnp
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- snrpn
- ssnrnp
- snrrnp
- snrnnp
- snrnpp
- cNRNP
- qNRNP
- rNRNP
- SlRNP
- SNbNP
- SNzNP
- SNvNP
- SNpNP
- SNsNP
- SNRfP
- SNRlP
- SNRoP
- SNRNx
- SNRNt
- SNRNr
- s nrnp
- sn rnp
- snr np
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