TISSUE TYPING Meaning and
Definition
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Tissue typing, also known as histocompatibility typing or human leukocyte antigen (HLA) typing, is a laboratory technique used to determine the compatibility of tissues or organs for transplantation. It is particularly important in organ and bone marrow transplants, as matching the donor and recipient tissues can significantly improve the success rate of the transplantation procedure.
The human leukocyte antigen system is a group of proteins located on the surface of cells that play a crucial role in the immune system. These proteins help distinguish between self and non-self cells, and any mismatch can lead to rejection of transplanted tissues or organs. Therefore, tissue typing involves testing the HLA proteins on both the donor and recipient cells to ensure compatibility.
The process of tissue typing begins with collecting blood samples from the donor and recipient. The blood cells are then isolated, and the HLA proteins are identified through various techniques, such as polymerase chain reaction (PCR), serology, or DNA sequencing. By comparing the HLA profiles of the donor and recipient, tissue typing determines the degree of compatibility.
Tissue typing is essential in transplant medicine, as it helps minimize the risk of rejection reactions by selecting donors with the closest HLA match to the recipient. It plays a crucial role in finding suitable donors, improving transplant success rates, and enhancing the long-term survival of transplanted tissues or organs.
Common Misspellings for TISSUE TYPING
- rissue typing
- fissue typing
- gissue typing
- yissue typing
- 6issue typing
- 5issue typing
- tussue typing
- tjssue typing
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- tiasue typing
- tizsue typing
- tixsue typing
- tidsue typing
- tiesue typing
- tiwsue typing
- tisaue typing
Etymology of TISSUE TYPING
The word "tissue typing" is a compound term consisting of two parts: "tissue" and "typing". Here's a breakdown of their etymologies:
1. Tissue:
The word "tissue" originates from the Middle English word "tissu", which means "a woven cloth". It came into English from the French word "tissu" and Latin word "texere", which means "to weave".
2. Typing:
"Typing" refers to the act of classifying or identifying something based on specific characteristics. It comes from the word "type", which has its roots in the Latin word "typus", meaning "figure, image, or type".
When combined, "tissue typing" refers to the classification or identification of tissues based on certain characteristics, commonly used in medical contexts like organ or cell transplantation.
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