DNA GYRASE B SUBUNIT Meaning and
Definition
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DNA gyrase B subunit is an essential protein component of the DNA gyrase complex. DNA gyrase is a type II topoisomerase enzyme that plays a crucial role in DNA replication and repair. The gyrase complex consists of two gyrase A subunits and two gyrase B subunits. Gyrase B subunit, being one of the two subunits, is responsible for the catalytic activity of the enzyme.
The DNA gyrase B subunit possesses a unique ATP-binding domain, which enables it to bind and hydrolyze ATP molecules. This ATPase activity is indispensable for the gyrase complex to introduce negative supercoils into DNA by cutting and resealing the DNA strands. The cleavage and re-ligation of DNA by DNA gyrase help in relieving the torsional stress generated during DNA replication and transcription.
The DNA gyrase B subunit is also involved in binding DNA and recognizing specific DNA sites known as gyrase-binding sites. These sites have a characteristic DNA sequence that facilitates the interaction between the enzyme and DNA. The binding of gyrase B subunit to these sites enables the enzyme to initiate its catalytic activity efficiently.
Overall, the DNA gyrase B subunit is an essential component of the DNA gyrase complex responsible for managing DNA supercoiling, maintaining DNA integrity, and facilitating various DNA-dependent processes such as replication, transcription, and recombination. The importance of the DNA gyrase B subunit in DNA metabolism makes it an attractive target for several antibiotics that inhibit bacterial gyrase activity, making it an important target for antimicrobial drug development.
Common Misspellings for DNA GYRASE B SUBUNIT
- sna gyrase b subunit
- xna gyrase b subunit
- cna gyrase b subunit
- fna gyrase b subunit
- rna gyrase b subunit
- ena gyrase b subunit
- dba gyrase b subunit
- dma gyrase b subunit
- dja gyrase b subunit
- dha gyrase b subunit
- dnz gyrase b subunit
- dns gyrase b subunit
- dnw gyrase b subunit
- dnq gyrase b subunit
- dna fyrase b subunit
- dna vyrase b subunit
- dna byrase b subunit
- dna hyrase b subunit
- dna yyrase b subunit
- dna tyrase b subunit
Similar spelling word for DNA GYRASE B SUBUNIT
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